Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner

Table 1 Correlation between TKT level and clinicopathological characteristics of 286 HCC patients

Clinicopathological variables		TKT level (High vs. Low)				p Value
		High level		Low level
		Mean	Count	Mean	Count
Age		51		53
Sex	Female		20		30	0.337
	Male		112		124
Cirrrhosis	Absent		99		118	0.759
	Present		32		35
Maximal tumor size	< 5 cm		98		117	0.735
	≥ 5 cm		34		37
Tumor number	Single		123		145	0.735
	Multiple		9		9
HBV infection	no		4		10	0.176
	yes		128		144
Anti_HCV	negtive		132		153	0.354
	positive		0		1
TB	< 20 μM/L		104		106	0.057
	≥ 20 μM/L		28		48
AFP	< 20 ng/mL		46		53	0.939
	≥ 20 ng/ml		86		101
Microvascular invasion	absent		65		113	< 0.001*
	present		67		41
Loss of Tumor encapsulation	Complete		60		90	0.028*
	Not complete		72		64
Child-pugh score	A Class		20		31	0.233
	B or C Class		109		116
TNM stage	I-II		118		149	0.013*
	III-IV		14		5

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