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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway

Fig. 7

NF inhibited the growth of U251 xenograft tumors in nude mice. a-d U251 cells were subcutaneously injected into the mouse left flank to establish xenograft models. After NF treatments (15 mg/kg, once a day for a total of 2 weeks), all mice were observed, and the tumor weight and volume were measured and compared. **P < 0.01 vs. control group. e Expression of Ki67, CDC2, Bcl-2, HIF1A, and N-cadherin in xenograft tumors were analyzed by immunohistochemistry (original magnification: × 400, scale bar: 100 μm). f Ultrasonography evaluation included B-mode, CDFI, CPA, and USE. g T1WI, T2WI, T2-FLAIR, and T2-SPIR imaging of tumors by MRI

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