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Table 1 Correlations Between TRIM44 with Clinicopathologic Features in 197 Melanoma Patients

From: TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4

Variable Number of Patients P value*
TRIM44low TRIM44high
Age, year
  < 60 36 42 0.351
  ≥ 60 63 56
Gender
 Male 49 56 0.282
 Female 50 52
Anatomic site
 Acra 48 53 0.395
 Trunk 22 26
 Other 29 21
Histologic type
 Superfical spreading 27 19 0.287
 Nodular 23 18
 Acral 29 40
 Lentigo maligna 20 21
Ulceration
 Present 15 11 0.416
 Absent 84 87
Breslow depth (mm)
  ≤ 2 49 64 0.025
  > 2 50 34
Clark level
 I-III 54 53 0.948
 IV-V 45 45
Lymph nodes metastasis
 No 69 73 0.453
 Yes 30 25
Distant metastasis
 No 82 66 0.012
 Yes 17 32
Clinical stage
 I-II 73 51 0.002
 III-IV 26 47
  1. Note: A chi-square test was used for comparing groups between low and high TRIM44 expression. *, p < 0.05 was considered significant