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Table 1 Correlations Between TRIM44 with Clinicopathologic Features in 197 Melanoma Patients

From: TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4

Variable

Number of Patients

P value*

TRIM44low

TRIM44high

Age, year

  < 60

36

42

0.351

  ≥ 60

63

56

Gender

 Male

49

56

0.282

 Female

50

52

Anatomic site

 Acra

48

53

0.395

 Trunk

22

26

 Other

29

21

Histologic type

 Superfical spreading

27

19

0.287

 Nodular

23

18

 Acral

29

40

 Lentigo maligna

20

21

Ulceration

 Present

15

11

0.416

 Absent

84

87

Breslow depth (mm)

  ≤ 2

49

64

0.025

  > 2

50

34

Clark level

 I-III

54

53

0.948

 IV-V

45

45

Lymph nodes metastasis

 No

69

73

0.453

 Yes

30

25

Distant metastasis

 No

82

66

0.012

 Yes

17

32

Clinical stage

 I-II

73

51

0.002

 III-IV

26

47

  1. Note: A chi-square test was used for comparing groups between low and high TRIM44 expression. *, p < 0.05 was considered significant