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Table 1 Correlations between expression of TRIM47 protein and clinicopathological factors

From: TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4

Clinicopathological feature Total
100
Expression of TRIM47 P value
2 test)
Low
(n = 24,24%)
High
(n = 76,76%)
Age(years)
 < 65 48 10(41.7) 38(50.0) 0.476
 ≥65 52 14(58.3) 38(50.0)
Gender
 Male 67 18(75.0) 49(64.5) 0.339
 Female 33 6(25.0) 27(35.5)
Tumor location
 Rectum 47 11(45.8) 36(47.4) 0.895
 Colon 53 13(54.2) 40(52.6)
Tumor size
 <30cm3 68 21(87.5) 47(61.8) 0.019
 ≥30 cm3 32 3(12.5) 29(38.2)
Histological differentiation
 Well/moderate 23 10(41.7) 13(17.1) 0.013
 Poor 77 14(58.3) 63(82.9)
T classification
 T1,2 21 9(37.5) 12(15.8) 0.023
 T3,4 79 15(62.5) 64(84.2)
TNM stage(AJCC)
 Stage I, II 43 6(25.0) 37(48.7) 0.041
 Stage III, IV 57 18(75.0) 39(51.3)
Invasive depth
 Mucous/muscular layer 20 8(33.3) 12(15.8) 0.080
 Serosa 80 16(66.7) 64(84.2)
Lymph node metastasis
 Absent 57 18(75.0) 39(51.3) 0.041
 Present 43 6(25.0) 37(48.7)
Distant metastasis
 Absent 86 22(91.7) 64(84.2) 0.508
 Present 14 2(8.3) 12(15.8)
Vascular invasion
 Absent 69 19(79.2) 50(65.8) 0.217
 Present 31 5(20.8) 26(34.2)