Fig. 1
From: Sox11 promotes head and neck cancer progression via the regulation of SDCCAG8
Upregulation of Sox11 in primary and recurrent HNSCC tissues and highly invasive HNSCC cells. (a) Relative Sox11 gene expression in 20 primary HNSCC (oral cancer) tissues analyzed by qRT-PCR. ***, P < 0.001 compared with eight normal tissues. (b) Relative Sox11 gene expression in four paired primary and recurrent HNSCC (oral cancer, same patients) tissues analyzed by qRT-PCR. ***, P < 0.001 compared with primary tissues. (c) SOX11 expression in four paired primary and recurrent HNSCC (oral cancer) tissues analyzed by western blotting. (d) IHC analysis of SOX11 expression in paired normal, primary and recurrent HNSCC (oral cancer) tissues. (e) Western blot analysis of SOX11 expression in four HNSCC cell lines (UM1, UM2, UMSCC5 and UMSCC6). (f) qPCR analysis of Sox11 gene expression in UM1, UM2, UMSCC5 and UMSCC6 cell lines. ***, P < 0.001 (UM1/UMSCC5 versus UM2/UMSCC6)