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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Sox11 promotes head and neck cancer progression via the regulation of SDCCAG8

Fig. 6

SDCCAG8 promotes HNSCC cell migration/invasion and partially rescues the inhibitory effects of Sox11 knockdown. (a) MTS assays of SDCCAG8 knockdown UM1/USCC5 cells or SDCCAG8 overexpression UM2/UMSCC6 cells. (b) Invasion and migration assays of SDCCAG8 knockdown UM1/USCC5 cells or SDCCAG8 overexpression UM2/UMSCC6 cells. (c) Western blot analysis of SOX11 and SDCCAG8 in UM1 and UMSCC5 cells with SOX11 knockdown or with both SOX11 knockdown and SDCCAG8 overexpression. (d) MTS assays of UM1 and UMSCC5 cells with either SOX11 knockdown or with both SOX11 knockdown and SDCCAG8 overexpression. (e) Invasion and migration assays of UM1 or UMSCC5 cells with either SOX11 knockdown or with both SOX11 knockdown and SDCCAG8 overexpression. Data are measured in triplicates. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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