Table 1 Relationship between Autophagy markers and clinicopathological features in 137 gastric cancer cases
From: Autophagy inhibition enhances PD-L1 expression in gastric cancer
LC3 | p62/SQSTM1 | |||||
|---|---|---|---|---|---|---|
High | Low | High | Low | |||
(n = 71) | (n = 66) | p value | (n = 42) | (n = 95) | p value | |
Parameter | ||||||
Age | ||||||
≤ 59 | 34 (50%) | 40 (50%) | 0.161 | 28 (41.1%) | 46 (58.9%) | 0.045 |
> 59 | 37 (62.7%) | 26 (37.2%) | 14 (22.9%) | 49 (77.1%) | ||
Gender | ||||||
Male | 55 (57.2%) | 46 (42.7%) | 0.883 | 36 (37.9%) | 65 (62.1%) | 0.099 |
Female | 16 (51.6%) | 20 (48.3%) | 6 (17.6%) | 30 (82.3%) | ||
Tumor site | ||||||
Proximal | 30 (62.5%) | 20 (37.5%) | 0.562 | 16 (33.3%) | 34 (66.6%) | 0.677 |
Antral | 41 (51.9%) | 46 (48.1%) | 26 (32%) | 61 (68%) | ||
TNM | ||||||
I-II | 41 (48%) | 39 (52%) | 0.725 | 24 (24%) | 56 (75%) | 0.413 |
III-IV | 30 (52.7%) | 27 (47.3%) | 18 (34%) | 39 (66%) | ||
Lauren’s classification | ||||||
Intestinal-type | 34 (60.7%) | 26 (39.3%) | 0.059 | 15 (26.7%) | 45 (73.3) | 0.013 |
Diffuse/mixed-type | 37 (52.1%) | 40 (47.9%) | 27 (40%) | 50 (60%) | ||
MLI | ||||||
Yes | 33 (46.6%) | 11 (53.3%) | 0.000052 | 23 (19.4%) | 70 (80.5%) | 0.015 |
No | 38 (69%) | 55 (31%) | 19 (51.9) | 25 (48.1%) | ||