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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

Fig. 3

Overexpression of G0S2 reduces glioma radiation response. a WB analysis of overexpression of G0S2 in U87, LN229 and U251 cells. b Clonogenic survival assay of U87, LN229 and U251 cells transduced with an empty vector (Control) or G0S2. Colonies formed by surviving cells 26 days after IR are shown. Error bars, SD. *, p < 0.05. c. Survival curves for mice implantation with 5 × 105 cells of U87/Control or U87 /G0S2 and left untreated or given daily dosed 2.5 Gy IR from day 14 to 17 after cell implantation. Arrows, IR treatment times. Data represent two independent experiments with 6 mice per group with similar results. d Clonogenic survival assay. Colonies formed by surviving cells 26 days with TMZ treatment are shown. Error bars, SD. *, p < 0.05

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