Skip to main content
Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Xenotropic and polytropic retrovirus receptor 1 (XPR1) promotes progression of tongue squamous cell carcinoma (TSCC) via activation of NF-κB signaling

Fig. 4

Silencing of XPR1 inhibits tumorigenecity of TSCC cells in vivo. (a) 5 × 106 SCC-25 control and shRNAs-mediated XPR1 knockdown cells were subcutaneously injected into Balb/c nude mice and inocubated for 7 weeks. Tumors in each group were shown. (b) Tumor volumes were calculated weekly. (c) Tumor weights in each group. (d) IHC staining of XPR1 and Ki67, as well as TUNEL staining in xenograft section. Proliferation index was indicated by Ki67-positive cell percentage. Apoptotic index was calculated by the percentage of TUNEL-positive cells. *P < 0.05, **P < 0.01

Back to article page