Fig. 2From: ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathwayACE2 inhibits breast cancer cell migration. (a) Basal expression of ACE2 in breast cancer cell lines. (b) mRNA level of ACE2 in MDA-MB-231 cells overexpressing ACE2 and ACE2-knockdown MCF-7 cells. (c) Protein levels of ACE2 in MDA-MB-231 cells overexpressing ACE2 and ACE2-knockdown MCF-7 cells. (d) Transwell migration assay of transfected MDA-MB-231 and MCF-7 cells. (e) CCK8 proliferation assay of transfected MDA-MB-231 and MCF-7 cells. Microscope magnification: 50×. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001Back to article page