Fig. 3
From: ACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway
ACE2 inhibits breast cancer angiogenesis in vitro. (a) Bubble plot of ACE2 and breast cancer angiogenesis obtained from the GO enrichment analysis. (b) Proliferation of HUVECs after 72 h in the TCM from transfected MDA-MB-231 and MCF-7 cells. (c) Tube formation ability of HUVECs cultivated for 6 h in the TCM from transfected MDA-MB-231 and MCF-7 cells. (d) Wound healing ability of HUVECs after 48 h in the TCM from transfected MDA-MB-231 and MCF-7 cells. Microscope magnification: 50×. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001