Fig. 1

Identification of GTSE1 in breast cancer progression based on database. a Expression level of GTSE1 was elevated in 1096 breast cancer tissues compared with 112 normal breast tissue samples in the TCGA profile. b GTSE1 expression was significantly upregulated in different breast cancer pathological types in TCGA profile based on the Oncomine (c, d, e and f) and bc-GenExMiner v4.1 databases. c GTSE1 expression was positively correlated with the degree of malignancy of different breast cancer subtypes. d GTSE1 expression was positively correlated with the Nottingham Prognostic Index (NPI) of breast cancer. e Metastatic relapse-free survival for patients with high or low GTSE1 mRNA expression. n = 3826, p < 0.0001, HR = 1.47. f GTSE1 low expression had a significantly better survival rate than that of high-expression patients. n = 5439, p < 0.0001, HR = 1.39