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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Fig. 6

a Heatmap representation of genes deregulated after SNHG15 depletion by siRNA in LoVo cells (p value < 0.01). b Molecular and cellular functions and diseases associated with these genes. P values are the min and max p values of the enriched categories within a general category that appears in the data Table. c Top canonical pathways changed after depletion of SNHG15 recognized by IPA. d qRT-PCR analysis for RNA-seq validation on the genes selected from RNA-seq and pathway analysies. P value is calculated by two-tailed Student’s t-test and graphs shows mean ± SEM of values (*p < 0.05, **p < 0.01, ***p < 0.001)

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