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Table 1 Clinicopathological features of HGSOC tissues with regard to the relative expression of Fn14

From: Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting Mdm2-mediated p53-R248Q ubiquitination and degradation

Patients’ characteristics

Total

Fn14 IHC (n)

P

n

low expression

high expression

71

(n = 48, 67.6%)

(n = 23, 43.3%)

Age(y)

  ≤ 50

19

10 (52.6%)

9 (47.4%)

0.152

 >50

52

38 (73.1%)

14 (26.9%)

FIGO stage

 I-II

8

1 (12.5%)

7 (87.5%)

0.001

 III-IV

63

47 (74.6%)

16 (25.4%)

Ascites

 positive

58

41 (70.7%)

17 (29.3%)

0.327

 negative

13

7 (53.8%)

6 (46.2%)

Residual lesions

 <2 cm

62

42 (67.7%)

20 (32.3%)

> 0.999

  ≥ 2 cm

9

6 (66.7%)

3 (33.3%)