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Table 1 Clinicopathological features of HGSOC tissues with regard to the relative expression of Fn14

From: Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting Mdm2-mediated p53-R248Q ubiquitination and degradation

Patients’ characteristics Total Fn14 IHC (n) P
n low expression high expression
71 (n = 48, 67.6%) (n = 23, 43.3%)
Age(y)
  ≤ 50 19 10 (52.6%) 9 (47.4%) 0.152
 >50 52 38 (73.1%) 14 (26.9%)
FIGO stage
 I-II 8 1 (12.5%) 7 (87.5%) 0.001
 III-IV 63 47 (74.6%) 16 (25.4%)
Ascites
 positive 58 41 (70.7%) 17 (29.3%) 0.327
 negative 13 7 (53.8%) 6 (46.2%)
Residual lesions
 <2 cm 62 42 (67.7%) 20 (32.3%) > 0.999
  ≥ 2 cm 9 6 (66.7%) 3 (33.3%)