Table 1 Baseline characteristics and Correlation analysis for clinicopathologic variables between EIF4A2-low and EIF4A2-high groups of 297 CRC patients
Variable | Total (%) | low EIF4A2 n (%) | high EIF4A2 n (%) | P value |
|---|---|---|---|---|
Total | 297 (100) | 172 (57.9) | 125 (42.1) | Â |
Age, years | Â | Â | Â | 0.557 |
  >  57 | 137(46.1) | 82 (47.7) | 55 (44.0) |  |
  ≤ 57 | 160(53.9) | 90 (52.3) | 70 (56.0) |  |
Gender | Â | Â | Â | 0.469 |
 male | 185 (62.3) | 104 (60.5) | 81 (64.8) |  |
 female | 112(37.7) | 68 (39.5) | 44 (35.2) |  |
Lymph node metastasis | Â | Â | Â | 0.184 |
 N0–1 | 218(73.4) | 121 (69.2) | 97 (77.6) |  |
 N2 | 79(26.6) | 51 (30.8) | 28 (22.4) |  |
Nerve invasion | Â | Â | Â | 0.078 |
 No | 152 (51.2) | 96 (55.8) | 56 (44.8) |  |
 Yes | 145 (48.8) | 76 (44.2) | 69 (55.2) |  |
Invasion depth | Â | Â | Â | 0.115 |
 No whole layer | 29 (9.8) | 21 (12.2) | 8 (6.4) |  |
 Whole layer | 268 (90.2) | 151 (87.8) | 117 (93.6) |  |
Vascular thrombosis | Â | Â | Â | 0.252 |
 No | 206 (69.4) | 124 (72.1) | 82 (65.6) |  |
 Yes | 91 (30.6) | 48 (27.9) | 43 (34.4) |  |
Metastasis status | Â | Â | Â | 0.031 |
 No | 245 (82.5) | 149 (86.6) | 96 (76.8) |  |
 Yes | 52 (17.5) | 23 (13.4) | 29 (23.2) |  |
Degree of differentiation | Â | Â | Â | 0.674 |
 Well and moderately differentiated | 230 (77.4) | 135 (78.5) | 95 (76.0) |  |
 Poorly differentiated | 67 (22.6) | 37 (21.5) | 30 (24.0) |  |
TNM stage | Â | Â | Â | 0.003 |
 I | 20 (6.7) | 12 (7.0) | 8 (6.4) |  |
 II | 87 (29.3) | 42 (24.4) | 45 (36.0) |  |
 III | 138 (46.5) | 95 (55.2) | 43 (34.4) |  |
 IV | 52 (17.5) | 23 (13.4) | 29 (23.2) |  |