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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia

Fig. 1

Expressional profile of FUT family in CD34 + CD38- AML cell lines. a The pre-sorting and post-sorting sub-populations were detected by flow cytometry. b The intensity of LSCs surface markers (CD13, CD33, CD123 and P-gp) were detected in KG-1a and MOLM13 cells. c Higher FUT4, FUT5, FUT8, FUT9 and FUT11 levels were detected in LSCs-KG-1a cells than the non-LSCs-KG-1a cells. d Elevated FUT2, FUT4, FUT5, FUT8, FUT9 and FUT11 levels were determined in LSCs-MOLM13 cells. e Upregulated FUT4 protein level was detected by western blot in LSCs and non-LSCs of KG-1a. f Higher FUT4 protein level was detected in LSCs than non-LSCs of MOLM13 cells by western blot. Data are the means ± SD of triplicate determinants (*P < 0.05)

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