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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma

Fig. 2

AGAP2-AS1 promotes cell proliferation, migration, invasion, EMT progress and inhibits apoptosis in HCC cells in vitro. a Hep3B and HCCLM3 cells that were transfected with corresponding lncRNA vectors were subjected to qRT-PCR for AGAP2-AS1 expression. Overexpression of AGAP2-AS1 promoted cell proliferation (b), migration (c), invasion (d) and inhibited apoptosis (e) in Hep3B cells, while down-regulation of AGAP2-AS1 inhibited cell proliferation (b), migration (c), invasion (d) and promoted apoptosis (e) in HCCLM3 cells. f Western blot analysis of EMT-related markers expression in the presence and absence of AGAP2-AS1. n = six independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001

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