Skip to main content
Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma

Fig. 9

AKT phosphorylation is essential for the biological function of ANXA11 in HCC. a HCCLM3 and Hep3B cells that were transfected with corresponding ANXA11 vectors were subjected to immunoblotting for phosphorylated AKT and AKT. AKT inhibitor MK2206, or AKT phosphorylation activator IGF-1, abolished the cell proliferation (b), migration (c), invasion (d), apoptosis (e) and EMT process (f) of HCC cells which were transduced of ANXA11 vectors. *P < 0.05

Back to article page