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Table 1 Correlation between the clinicopathologic characteristics and lncRNA AGAP2-AS1 and miR-16-5p expression in HCC (n = 137)

From: RETRACTED ARTICLE: Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma

Clinical parameters

Cases

Expression level

P value

Expression level

 

P value

AGAP2-AS1high

(n = 69)

AGAP2-AS1low

(n = 68)

miR-16-5phigh

(n = 66)

miR-16-5plow

(n = 71)

Age(years)

  < 65 years

76

40

36

0.554

35

41

0.579

  ≥ 65 years

61

29

32

 

31

30

 

Gender

 Male

109

55

54

0.965

53

56

0.836

 Female

28

14

14

 

13

15

 

Tumor size (cm)

 <5 cm

108

48

60

0.007*

59

49

0.004*

 ≥ 5 cm

29

21

8

 

7

22

 

Tumor number

 solitary

119

59

60

0.637

57

62

0.868

 multiple

18

10

8

 

9

9

 

Edmondson

 I + II

98

41

57

0.002*

50

48

0.291

 III + IV

39

28

11

 

16

23

 

TNM stage

 I + II

110

50

60

0.020*

58

52

0.031*

 III + IV

27

19

8

 

8

19

 

Capsular

 Present

93

47

46

0.953

46

47

0.661

 Absent

44

22

22

 

20

24

 

Venous invasion

 Present

18

14

4

0.013*

3

15

0.004*

 Absent

119

55

64

 

63

56

 

AFP

 <400 ng/ml

36

21

15

0.265

17

19

0.894

 ≥ 400 ng/ml

101

48

53

 

49

52

 

HBsAg

 positive

123

61

62

0.592

59

64

0.885

 negative

14

8

6

 

7

7

 
  1. HCC hepatocellular carcinoma, AFP alpha-fetoprotein, TNM tumor-node-metastasis
  2. *Statistically significant is in bold
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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