Skip to main content

Table 1 Correlations between the expression of miR-let-7b / miR-let-7c and patient characteristics

From: miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Clinical characteristics Expression of miR-let-7b / miR-let-7c P value
Low (n = 46,%) High (n = 60,%)
Gender Male 21 (40.4) 31 (56.6) 0.54
Female 25 (46.3) 29 (53.7)
Age > 60 18 (40) 27 (60) 0.55
≤60 28 (45.9) 33 (54.1)
Initial stage I + II 20 (46.5%) 23 (53.5%) 0.92
III + IV 25 (45.5%) 30 (54.4%)
Metastasis With 24 (58.5) 17 (41.5) 0.11
(Liver/Brain) Without 6 (35.3) 11 (64.7)
Thickness < 4 mm 1 (20.0) 4 (80.0) 0.91
≥4 mm 9 (42.9) 12 (57.1)
Ulcer With 11 (28.9) 27 (71.1) 1.00
Without 2 (25.0) 6 (75.0)
LDH < 240 IU/L 26 (45.6) 31 (54.4) 0.78
≥240 IU/L 17 (48.6) 18 (51.4)
ECOG 0 9 (27.3) 24 (72.7) 0.01
1 32 (57.1) 24 (42.9)
2 2 (50) 2 (50)
BRAF status Wild type 43 (45.7) 51 (54.3) 0.17
Mutant type 2 (25.0) 10 (75.0)
CKIT status Wild type 41 (42.3) 56 (57.7) 0.91
Mutant type 5 (55.6) 4 (44.4)
NRAS status Wild type 32 (41.2) 45 (58.8) 0.44
Mutant type 11 (52.4) 10 (47.6)
PDGFR status Wild type 43 (44.8) 53 (55.2) 1.00
Mutant type 1 (50) 1 (50)
  1. Initial stage Stage of initial diagnosis, LDH Lactate dehydrogenase, ECOG Eastern Cooperative Oncology Group, P < 0.05 indicates statistically significant in bold