Table 1 Correlations between the expression of miR-let-7b / miR-let-7c and patient characteristics
Clinical characteristics | Expression of miR-let-7b / miR-let-7c | P value | ||
|---|---|---|---|---|
Low (n = 46,%) | High (n = 60,%) | |||
Gender | Male | 21 (40.4) | 31 (56.6) | 0.54 |
Female | 25 (46.3) | 29 (53.7) | ||
Age | > 60 | 18 (40) | 27 (60) | 0.55 |
≤60 | 28 (45.9) | 33 (54.1) | ||
Initial stage | I + II | 20 (46.5%) | 23 (53.5%) | 0.92 |
III + IV | 25 (45.5%) | 30 (54.4%) | ||
Metastasis | With | 24 (58.5) | 17 (41.5) | 0.11 |
(Liver/Brain) | Without | 6 (35.3) | 11 (64.7) | |
Thickness | < 4 mm | 1 (20.0) | 4 (80.0) | 0.91 |
≥4 mm | 9 (42.9) | 12 (57.1) | ||
Ulcer | With | 11 (28.9) | 27 (71.1) | 1.00 |
Without | 2 (25.0) | 6 (75.0) | ||
LDH | < 240 IU/L | 26 (45.6) | 31 (54.4) | 0.78 |
≥240 IU/L | 17 (48.6) | 18 (51.4) | ||
ECOG | 0 | 9 (27.3) | 24 (72.7) | 0.01 |
1 | 32 (57.1) | 24 (42.9) | ||
2 | 2 (50) | 2 (50) | ||
BRAF status | Wild type | 43 (45.7) | 51 (54.3) | 0.17 |
Mutant type | 2 (25.0) | 10 (75.0) | ||
CKIT status | Wild type | 41 (42.3) | 56 (57.7) | 0.91 |
Mutant type | 5 (55.6) | 4 (44.4) | ||
NRAS status | Wild type | 32 (41.2) | 45 (58.8) | 0.44 |
Mutant type | 11 (52.4) | 10 (47.6) | ||
PDGFR status | Wild type | 43 (44.8) | 53 (55.2) | 1.00 |
Mutant type | 1 (50) | 1 (50) | ||