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Table 2 Comparison of PD-L1 expression levels within ADC study group

From: PD-L1 expression and tumor mutational burden status for prediction of response to chemotherapy and targeted therapy in non-small cell lung cancer

Characteristic PD-L1 expression
TC IC
Negative (n, %) Any+ (n, %) P value Negative (n, %) Any+ (n, %) P value
Age (years) 0.380   0.719
 <58 43 67% 21 33%   40 63% 24 38%  
 ≥58 43 60% 29 40% 48 67% 24 33%  
Sex <0.001   0.854
 Male 45 52% 41 48%   55 64% 31 36%  
 Female 41 82% 9 18% 33 66% 17 34%  
Smoking status 0.186   0.508
 Never smoker 72 66% 37 34%   72 66% 37 34%  
 Smoker 14 52% 13 48% 16 59% 11 41%  
Pathologic stage 0.586   0.098
 IIIB 36 67% 18 33%   30 56% 24 44%  
 IV 50 61% 32 39% 58 71% 24 29%  
Mutation status 0.049   0.475
 EGFR mutant 43 74% 15 26%   38 66% 20 34%  
 KRAS mutant 11 65% 6 35% 13 76% 4 24%  
 Other 32 52% 29 48% 37 61% 24 39%