Fig. 2

Long non-coding RNA TPTEP1 suppresses HCC cell proliferation and invasion. a Cell proliferation was examined by MTT assays in TPTEP1-knockdowned QGY-7703 cells (shRNA- TPTEP1) or TPTEP1-overexpressed MHCC97H cells (LV-TPTEP1) at the indicated time points. The shRNA-Control QGY-7703 cells or LV-Control MHCC97H cells were as control. b Tumor colony numbers were examined by colony formation assays in TPTEP1-knockdowned QGY-7703 cells (shRNA-TPTEP1) or TPTEP1-overexpressed MHCC97H cells (LV-TPTEP1). c Cell invasive ability was examined by transwell invasion assays in TPTEP1-knockdowned QGY-7703 cells (shRNA-TPTEP1) or TPTEP1-overexpressed MHCC97H cells (LV-TPTEP1). d Cell apoptotic rates were analyzed by flow cytometry in TPTEP1-knockdowned QGY-7703 cells (shRNA-TPTEP1) or TPTEP1-overexpressed MHCC97H cells (LV-TPTEP1). Data are represented as means ± SD (n = 3; ^*represents P < 0.05)