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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism

Fig. 3

Monocytes exposed to senescent thyrocytes and thyroid tumor cell lines express M2-related genes. qRT-PCR analysis of genes related to M2 macrophage phenotype in monocytes treated with the conditioned medium from: a proliferating (PTh) and senescent (STh) thyrocytes; b normal thyroid cells (NThy) or tumor thyroid cell lines: BCPAP and HTC/C3. c Control macrophages: M0 (hrM-CSF-generated), M1 (stimulated with LPS and IFN-γ) and M2 (stimulated with IL-4). Results were normalized with 18S RNA levels and expressed as fold change relative to their respective controls: PTh in (a); NThy in (b), M0 in (c)

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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