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Table 1 p65BTK score of the NSCLC patients’ tissue analyzed by IHC

From: p65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma

p65BTK expression

All (382)

AdC (293)

SCC (89)

Smokers (283)

Non-smokers (65)

Negative

189 (49.3%)

129 (43.9%)

60 (67.4%)

151 (53.3%)

18 (27.7%)

1–10% positive cells

131 (34.2%)

106 (36%)

25 (28.1%)

101 (35.7%)

21 (32.3%)

11–20% positive cells

12 (3.1%)

10 (3.4%)

2 (2.2%)

5 (1.8%)

5 (7.7%)

21–50% positive cells

24 (6.3%)

23 (7.8%)

1 (1.1%)

15 (5.3%)

8 (12.1%)

51–100% positive cells

26 (6.8%)

25 (8.5%)

1 (1.1%)

11 (3.9%)

13 (20%)

Positive

193(50.4%)

164 (55.8%)

29 (32.6%)

132 (46.7%)

47 (72.3%)

  1. The analysis was performed on TMA using the antibody BN30, produced and characterized in the lab. AdC adenocarcinoma, SCC squamous cell carcinoma
  2. In bold are indicated the number of samples completely negative or positive (any positivity) for p65BTK expression