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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

Fig. 7

In vivo study. a. The sample tumors from respective groups were presented. b. Tumor xenograft growth curves in subcutaneous implantation assay were displayed. Data represent mean ± SD (n = 10, each group). **P < 0.01 vs. Control group, ##P < 0.01 vs. A1CF (−) group, &&P < 0.01 vs. FAM224A (−) group, ΨΨP < 0.01 vs. pre-miR-590-3p group. c. Survival curves from representative nude mice injected into the right striatum in orthotopic inoculations assay were exhibited. (log-rank test, P < 0.01, A1CF (−), FAM224A (−), pre-miR-590-3p and A1CF (−) + FAM224A (−) + pre-miR-590-3p groups versus Control group). d. The schematic diagram underlying the mechanism of A1CF/FAM224A/miR-590-3p/ZNF143 positive feedback loop in glioma cells

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