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Table 1 Intraperitoneal inject single-dose toxicity of EE02 in mice

From: A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation

Group

n

Dose (mg/kg b.w.)

Logarithmic Dose

Mortality

Mortality Rate (%)

Vehicle control group

10

5 (mL/kg b.w.)

0

0/10

0

1

10

75.00

1.875

0/10

0

2

10

86.25

1.936

3/10

30

3

10

99.19

1.996

4/10

40

4

10

114.07

2.057

7/10

70

5

10

131.18

2.118

9/10

90

6

10

150.85

2.179

10/10

100