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Table 1 Intraperitoneal inject single-dose toxicity of EE02 in mice

From: A low-molecular-weight compound exerts anticancer activity against breast and lung cancers by disrupting EGFR/Eps8 complex formation

Group n Dose (mg/kg b.w.) Logarithmic Dose Mortality Mortality Rate (%)
Vehicle control group 10 5 (mL/kg b.w.) 0 0/10 0
1 10 75.00 1.875 0/10 0
2 10 86.25 1.936 3/10 30
3 10 99.19 1.996 4/10 40
4 10 114.07 2.057 7/10 70
5 10 131.18 2.118 9/10 90
6 10 150.85 2.179 10/10 100