Fig. 7

Hyperglycemia promotes tumor growth and reduces NK cell function in vivo. a The experimental schema of generating diabetes mouse model. b The changes in blood glucose after STZ or insulin treatment in the mouse model. c The changes in tumor weight after STZ or insulin injection in the mouse model. d The changes in tumor volume after STZ or insulin injection in the mouse model. e Immunohistochemical staining of Bmi1, MICA/B, GATA2 and p-AMPK in tumor tissues. Data in the graphs represented means ± SD from three parallel experiments. Scale bar, 50 μm, **P < 0.01; *P < 0.05