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Table 1 IC 30 and IC50 values for SI113 in ADF, U373MG and T98G human GBM anchorage-dependent cell lines and for GBM3-Luc and GBM-I neurospheres

From: The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells

Cell line IC30 for SI113 (μM) IC50 for SI113 (μM)
ADF 10.4 19.7
U373MG 7.0 14.45
T98G 5.23 6.65
GBM3-Luc 9.47 19.15
GBM-I 9.10 17.21
  1. Values were determined by titrating the effect of the drug in a cell viability assay after 48 h of treatment. The data reported are the average of two different experiments performed in triplicate