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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: The roles of glucose metabolic reprogramming in chemo- and radio-resistance

Fig. 4

The role of the exosomes in the formation of CSCs. The cancer cells with enhanced glycolysis could release a large amount of exosomes contained several of glycolytic enzymes and CSCs markers. These exosomes can be taken up by the recipient cancer cells, and then promote the glycolysis and induce the dedifferentiation of cancer cells to acquire stemness phenotype through transfer their stemness-related molecules

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