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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming

Fig. 2

Hypo-MSC promotes HCC progression through COX2/PGE2 axis. a Protein levels of COX2 and PGE2 secreted by MSC under normal or hypoxia condition (n = 3). b Protein levels of COX2 and PGE2 secreted by MSC after COX2 knockdown by lentivirus under normal or hypoxia condition (n = 3). c The proliferation ability of 7402 and Hep3b under indicated conditions (n = 3). d-e Representative images and quantification of Edu positive cells in 7402 and Hep3b under indicated conditions (n = 3). f Images of xenograft tumors, tumor volume and weight measurement of 7402 or Hep3b injected alone or co-injected with MSC (n = 6). g The representative images of Ki-67 of xenograft tumors in 7402 or Hep3b injected alone or co-injected with MSC. (*p < 0.05, **p < 0.01, #p < 0.05 vs Ctrl, ##p < 0.01 vs Ctrl)

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