Skip to main content

Advertisement

Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming

Fig. 3

Hypo-MSC activates YAP signaling to promote cell proliferation in HCC cells. a Protein levels of YAP and its target CTGF in 7402 and Hep3b under indicated conditions. b The mRNA levels of YAP and its target genes (CTGF, CYR61) in 7402 and Hep3b under indicated conditions. c-d Immunofluorescence of YAP in in 7402 and Hep3b c and quantitative data percentage of cells with nuclear YAP (d, n = 3). e The representative images of YAP in xenograft tumors. f The proliferation ability of 7402 and Hep3b after YAP knockdown via siRNA under indicated conditions (n = 3). g Quantification of Edu positive cells in 7402 and Hep3b cells after YAP knockdown via siRNA under indicated conditions (n = 3). (*p < 0.05, **p < 0.01)

Back to article page