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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming

Fig. 7

Hypo-MSC promotes lipogenesis via EP4 mediated YAP activation in cells. a Cellular levels of TG in EP4 knockdown cells under indicated conditions (n = 3). b Protein levels of AKT, mTOR and SREBP1 in EP4 knockdown cells under indicated conditions. c The mRNA levels of lipogenic enzymes in EP4 knockdown cells under indicated conditions (n = 3). d The content of neutral lipids in EP4 knockdown cells under indicated conditions. e Proposed model for hypo-MSC on HCC progression. (*p < 0.05, **p < 0.01)

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