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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: DEPTOR induces a partial epithelial-to-mesenchymal transition and metastasis via autocrine TGFβ1 signaling and is associated with poor prognosis in hepatocellular carcinoma

Fig. 1

DEPTOR is overexpressed in HCC, and high expression of DEPTOR is associated with a poor prognosis in HCC patients. a IHC analysis of DEPTOR expression in 110 paired HCC tissues and adjacent non-tumor tissues. Representative images of DEPTOR expression are shown in the left panels. Scale bar, 300 μm (upper panel) or 20 μm (lower panel). b Statistical analysis of DEPTOR expression in HCC tissues and adjacent non-tumor tissues. c Western blot analysis of relative DEPTOR expression in 53 HCC tissues (T) and adjacent non-tumor tissues (N). d DEPTOR bands of HCC tissues were quantified and shown in the bar chart after being normalized to the respective adjacent non-tumor tissues. e Western blot analysis of DEPTOR expression in a normal liver cell line and eight HCC cell lines. f Kaplan-Meier analysis of the correlation between DEPTOR expression and overall survival (OS) of HCC patients. g Kaplan-Meier analysis of the correlation between DEPTOR expression and disease-free survival (g) of HCC patients

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