Fig. 2

Effect of silencing HIG2 on HCC cell migration and invasion in vitro. a HIG2 protein expression in HepG2 and SMMC-7721 cells transfected with siR-HIG2 or siR-NC, as determined by Western blotting. *P < 0.05. b Proliferation of HepG2 and SMMC-7721 cells transfected with siR-HIG2 or siR-NC, as determined by CCK-8 assay. *P < 0.05 compared with siR-NC at the same time points. c Migration and invasion of HepG2 and SMMC-7721 cells transfected with siR-HIG2 or siR-NC, as determined by Transwell assay. *P < 0.05 compared with the respective siR-NC group