Fig. 3

HCC tumors in nude mice induced by HIG2-silenced SMMC-7721 cells. a Volume of tumors in nude mice induced by SMMC-7721 cells transfected with siR-HIG2 or siR-NC. *P < 0.05 compared with the siR-NC group. b Lung metastasis count in siR-HIG2 and siR-NC groups. *P < 0.05 compared with siR-NC group. c Expression of the epithelial marker E-Cadherin and the interstitial marker Vimentin in tumors from the siR-HIG2 and siR-NC groups, as determined by immunohistochemistry