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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Hypoxia-inducible gene 2 promotes the immune escape of hepatocellular carcinoma from nature killer cells through the interleukin-10-STAT3 signaling pathway

Fig. 5

Effect of conditioned media from HIG2-silenced SMMC-7721 cells on the phenotype and function of NK cells. a Ratio of NK cells with positive expression of NKp30, NKG2D, CD16, NKp46, NKG2A, or 158b after treatment with the conditioned media of SMMC-7721 cells in the siR-HIG2 or siR-NC group. *P < 0.05 compared with the siR-NC group. b Ratio of NK cells with positive expression of Granzyme B, Perforin, TNF-α, or IFN-γ after treatment with the conditioned media of SMMC-7721 cells in the siR-HIG2 or siR-NC group. *P < 0.05 compared with the siR-NC group

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