Table 1 The clinicopathologic characteristics of AJAP1 expression in 283 Breast cancer patients
Parameters | Cases | AJAP1 | p | |
|---|---|---|---|---|
Low expression (N, %) | High expression (N, %) | |||
Age(yr) | 118(41.7) | 165(58.3) | ||
≤50 | 130 | 49(41.5) | 81(49.1) | 0.208 |
> 50 | 153 | 69(58,5) | 84(50.9) | |
Menopausal status | ||||
Premenopausal | 156 | 60(50.8) | 96(58.2) | 0.221 |
Postmenopausal | 127 | 58(49.2) | 69(41.8) | |
Family history | ||||
No | 194 | 85(72.0) | 109(66.1) | 0.286 |
Yes | 89 | 33(28.0) | 56(33.9) | |
Tumor size | ||||
T1 | 103 | 42(35.6) | 68(41.2) | 0.615 |
T2 | 148 | 66(55.9) | 83(50.3) | |
T3 | 32 | 10(8.5) | 14(8.5)) | |
Histological grade | ||||
1 | 44 | 9(7.6) | 35(21.2) | < 0.0001* |
2 | 153 | 59(50.0) | 94(57.0) | |
3 | 86 | 50(42.4) | 36(21.8) | |
LN involvement | ||||
0 | 180 | 65(55.1) | 115(69.7) | 0.010* |
1–3 | 43 | 19(16.1) | 24(14.5) | |
4–9 | 41 | 20(16.9) | 21(12.7) | |
≥ 10 | 19 | 14(11.9) | 5(3.0) | |
ER | ||||
Negative | 111 | 50(42.4) | 61(37) | 0.359 |
Positive | 172 | 68(57.6) | 104(63) | |
PR | ||||
Negative | 142 | 83(41.5) | 82(49.7) | 0.849 |
Positive | 141 | 35(42.2) | 83(50.3) | |
Her-2 | ||||
Negative | 200 | 83(41.5) | 117(58.5) | 0.917 |
Positive | 83 | 35(42.2) | 48(57.8) | |
Ki67 | ||||
< 20 | 83 | 31(26.3) | 52(31.5) | 0.339 |
≥ 20 | 200 | 87(73.7) | 113(68.5) | |
P53 | ||||
Negative | 143 | 59(50) | 84(50.9) | 0.880 |
Positive | 140 | 59(50) | 81(49.1) | |