Fig. 2

H. cordata and 2-undecanone protect BEAS-2B cells from B[a]P-induced cytotoxicity and proliferation inhibition. The cytotoxicity of H. cordata (6.25 to 200 mg/L, 48 h) (a) and 2-undecanone (6.25 to 200 μM, 48 h) (b) toward BEAS-2B cells was evaluated by using an MTT assay. The viability of BEAS.2B cells was also measured by MTT assay after treatment with H. cordata (3.125-100 mg/mL) (c) or 2-undecanone (6.25-200 μM) (d) for 48 h in the presence or absence of B[a]P (5 μM). e EdU incorporation was evaluated after treatment of cells with vehicle, B[a]P (5 μM) alone, B[a]P (5 μM) plus H.cordata (12.5, 25, or 50 mg/mL), or B[a]P (5 μM) plus 2-undecanone (25, 50, or 100 μM) for 48 h. The EdU-positive cells in each group were quantified as the percentage of those in the control group. The data represent the mean ± SD (n = 3). ^#p < 0.05 and ^###p < 0.001 compared with the control cells (given water); ^*p < 0.05 and ^***p < 0.001 compared with the model cells (given B[a]P)