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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Ubiquitin-specific protease 3 promotes cell migration and invasion by interacting with and deubiquitinating SUZ12 in gastric cancer

Fig. 3

USP3 promotes EMT and metastasis in vivo. a External whole-body fluorescence images of mice orthotopically transplanted with BCG-823 cells (n = 3 in each group). Representative images of metastatic loci in the lungs are shown. b The number of metastatic loci in the lungs was counted. c Metastatic cancer tissues were stained with H&E. d Expression of E-cadherin positivity in tumors derived from BCG-823 cells was determined by qRT-PCR. ****, P < 0.001. e E-cadherin expression in the lung metastasis of GC was detected by IHC. Scale bars, 100 μm in c and e

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