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Table 4 Multivariate Cox regression analysis for the overall survival and relapse-free survival of osteosarcoma patients

From: FAM83H is involved in stabilization of β-catenin and progression of osteosarcomas

Characteristics OS RFS
HR (95% CI) P HR (95% CI) P
Distant metastasis, presence (vs. absence) 9.669 (1.994–46.879) 0.005 6.577 (1.524–28.377) 0.012
Cy-FAM83H, positive (vs. negative) 15.463 (3.196–74.809) < 0.001 15.825 (3.461–72.358) <  0.001
  1. Abbreviations: Cy-FAM83H cytoplasmic expression of FAM83H, HR hazard ratio, 95% CI 95% confidence interval. The multivariate analysis was adjusted for age, tumor size, stage, histologic grade, lymph node metastasis, distant metastasis, nuclear FAM83H expression, cytoplasmic FAM83H expression, and β-catenin expression. HR hazard ratio, OS overall survival, RFS relapse-free survival