Fig. 3From: Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequencesMolecular mechanisms of ER stress unfolded protein response (UPR) pathways. The three main sensors of UPR, localized at the ER membrane, and activated are inositol-requiring enzyme 1α (IRE1α), PKR-like ER kinase (PERK), and activating transcription factor 6 (ATF6). The autophagy induction alleviates the ER stressBack to article page