Fig. 1

GINS4 is highly expressed in lung cancer tissues and is associated with the poor survival of patients with lung ADC. a qRT-PCR analysis of GINS4 expression in 79 lung cancer tissue samples and corresponding paired normal lung tissue samples. b and c IHC analysis was performed to determine GINS4 protein level in lung cancer and normal lung tissue samples (b). Mean values of IHC quantification of GINS4 protein level are shown for lung cancer tissue samples compared with those for normal lung tissue samples (c). d Western blotting analysis of GINS4 in 11 lung ADC cancer and normal lung tissue samples. e-g Kaplan–Meier curves for the overall survival rates of patients with (e) lung cancer, (f) lung ADCs, and (g) lung SCCs. **P < 0.01 and ***P < 0.001