Table 1 Clinical pathologic characteristics and chi-square analysis of OSCC patients
Clinical Variables | Total (%) | EREG in CAFs | χ2 | p value | OR | 95% CI | |
|---|---|---|---|---|---|---|---|
Low (%) | High (%) | ||||||
Total | 104 (100) | 61 (100) | 43 (100) | – | – | – | – |
Sex | |||||||
 Male | 51 (49.0) | 20 (32.8) | 31 (72.1) | 15.59 | < 0.0001*** | 0.1888 | 0.08035 to 0.4438 |
 Female | 53 (51.0) | 41 (67.2) | 12 (27.9) |  |  |  |  |
Age | |||||||
 <60 | 44 (42.3) | 21 (34.4) | 23 (53.5) | 3.755 | 0.0527 | 0.4565 | 0.2053 to 1.015 |
 ≥60 | 60 (57.7) | 40 (65.6) | 20 (46.5) |  |  |  |  |
TNM stage | |||||||
 T1-2N0M0 | 80 (76.9) | 53 (86.9) | 27 (62.8) | 8.248 | 0.0041** | 3.926 | 1.492 to 10.33 |
 T3-4N0M0 | 24 (23.1) | 8 (13.1) | 16 (36.2) |  |  |  |  |
Differentiation | |||||||
 Well | 67 (64.4) | 43 (70.5) | 24 (55.8) | 2.371 | 0.1236 | 1.891 | 0.8366 to 4.275 |
 Medium to poor | 37 (35.6) | 18 (29.5) | 19 (44.2) |  |  |  |  |
Perineural Infiltration | |||||||
 No | 88 (84.6) | 55 (90.2) | 33 (76.7) | 3.489 | 0.0618 | 2.778 | 0.9241 to 8.350 |
 Yes | 16 (15.4) | 6 (9.8) | 10 (23.3) |  |  |  |  |
DOI | |||||||
 <5 mm | 62 (59.6) | 48 (78.7) | 14 (32.6) | 22.29 | < 0.0001*** | 7.648 | 3.157 to 18.53 |
 ≥5 mm | 42 (40.4) | 13 (21.3) | 29 (67.4) |  |  |  |  |
WPOI | |||||||
 1–3 | 59 (56.7) | 46 (75.4) | 13 (30.2) | 20.97 | < 0.0001*** | 7.077 | 2.954 to 16.96 |
 4–5 | 45 (43.3) | 15 (24.6) | 30 (69.8) |  |  |  |  |