Fig. 1
From: A novel method to establish glucocorticoid resistant acute lymphoblastic leukemia cell lines
Resistance characteristics of CEM-C7/HDR and CEM-C7/H cell lines. a IC50 and RI of CEM-C7/HDR cells at 10~400 PDLs. Cells were cultured with increasing concentrations of Dex for 48 h. Cell viability was evaluated by MTT assays. The IC50 values were calculated by linear interpolation. Experiments were performed in triplicate. b IC50 and RI of CEM-C7/H cells at 10~400 PDLs. c IC50 and RI of subclones of CEM-C7/HDR cells. Four monoclones were screened. d IC50 and RI of subclones of CEM-C7/H cells. Four monoclones were screened. e Flow chart for constructing the GC-resistant cell lines