Fig. 6
From: NKAP alters tumor immune microenvironment and promotes glioma growth via Notch1 signaling
Correlated NKAP and Notch1 expression in glioma tissues. a, IHC was performed to detect NKAP and Notch1 expression in normal brain specimens and in grade I, II, III, and IV glioma specimens (400×). b, The intensity of Notch1 expression in glioma specimens significantly increased as tumor malignancy increased. c, A remarkable positive correlation between the expression of NKAP and Notch1 was observed in 90 glioma specimens (P < 0.01). d and e, The overall survival of the 90 glioma patients was assessed based on low or high expression levels of NKAP and Notch1. The higher expression of NKAP and Notch1 indicated a worse prognosis. Scale bar = 20 μm