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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux

Fig. 4

Knockdown of ATG4C suppressed autophagy and autophagic flux. a, b ATG4C stable knockdown glioma cells were established by lentivirus infection, and the interference efficiency was detected by Western blot analysis. c Protein expression of LC3-II and P62 in glioma cells transfected with si-ATG4C. d, e Knockdown of ATG4C on the expression of LC3-II in the presence of BafA1. f Transmission electron microscopy observation of cellular ultrastructure tin T98G cells by ATG4C depletion. Arrows indicate autophagic vacuoles. *p < 0.05, **p < 0.01, ***p < 0.001, NS: not significant

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