Fig. 9From: High glucose microenvironment accelerates tumor growth via SREBP1-autophagy axis in pancreatic cancerSchematic diagram illustrating how high glucose promotes PC growth. In high glucose microenvironment, SREPB1 is stimulated, after which proliferation is induced and apoptosis and autophagy are suppressed. Furthermore, autophagy promotes SREBP1 expression. Ultimately, this signaling cascade promotes PC growthBack to article page