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Table 4 Detailed description of TCGA tumor datasets having a statistically significant APE1/NPM1 gene expression correlation. Every cohort is represented by its symbol (as shown in Additional file 6: Figure S5), full description, RNA-seq gene expression correlation between APE1 and NPM1 and statistical significance of the data

From: APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC

Cohort

Description

Corr

P value

PRAD

Prostate adenocarcinoma

0.644

1.58E-59

KICH

Kidney Chromophobe

0.590

1.88E-07

PAAD

Pancreatic adenocarcinoma

0.517

1.41E-13

SARC

Sarcoma

0.503

5.22E-18

GBMLGG

Glioma

0.501

9.73E-44

THYM

Thymoma

0.462

1.07E-07

LUAD

Lung adenocarcinoma

0.448

8.68E-27

THCA

Thyroid carcinoma

0.445

1.00E-25

KIPAN

Pan-kidney cohort (KICH+KIRC+KIRP)

0.431

1.30E-41

KIRP

Kidney renal papillary cell carcinoma

0.431

1.48E-14

STES

Stomach and Esophageal carcinoma

0.415

2.24E-26

STAD

Stomach adenocarcinoma

0.412

1.77E-18

ESCA

Esophageal carcinoma

0.398

2.28E-08

KIRC

Kidney renal clear cell carcinoma

0.392

5.52E-21

CESC

Cervical squamous cell carcinoma and endocervical adenocarcinoma

0.380

7.13E-12

UCEC

Uterine Corpus Endometrial Carcinoma

0.369

4.73E-19

LIHC

Liver hepatocellular carcinoma

0.348

5.09E-12

COAD

Colon adenocarcinoma

0.344

3.87E-14

GBM

Glioblastoma multiforme

0.306

1.17E-04

COADREAD

Colorectal adenocarcinoma

0.291

1.25E-13

BRCA

Breast invasive carcinoma

0.282

1.74E-21

SKCM

Skin Cutaneous Melanoma

0.270

5.76E-03

HNSC

Head and Neck squamous cell carcinoma

0.264

1.04E-09

LUSC

Lung squamous cell carcinoma

0.246

2.31E-08

BLCA

Bladder Urothelial Carcinoma

0.244

6.14E-07