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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

Fig. 7

Homoharringtonine (HHT) combined with arsenic trioxide (ATO) efficaciously eliminated the leukemia stem cells (LSCs) in a xenograft model of NRG mice (n = 5). (a) Evaluation of enrichment of KG-1 cells in the spleens and bone marrow of mice by analysis of hCD45 expression using flow cytometry. (b, c) Detection the residual of LSCs (CD34+CD38CD96+) in the spleens and bone marrow using flow cytometry. (d) Representative flow cytometric analysis of stem LSCs markers (CD34, CD38, CD96). P < 0.05*, P < 0.01**, P < 0.001***

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