Fig. 7From: Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanismsHomoharringtonine (HHT) combined with arsenic trioxide (ATO) efficaciously eliminated the leukemia stem cells (LSCs) in a xenograft model of NRG mice (n = 5). (a) Evaluation of enrichment of KG-1 cells in the spleens and bone marrow of mice by analysis of hCD45 expression using flow cytometry. (b, c) Detection the residual of LSCs (CD34+CD38−CD96+) in the spleens and bone marrow using flow cytometry. (d) Representative flow cytometric analysis of stem LSCs markers (CD34, CD38, CD96). P < 0.05*, P < 0.01**, P < 0.001***Back to article page