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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

Fig. 6

ADAR1 promoted tumor growth and stemness in the nude mouse xenograft model. a Image representing the volume of tumors after injection in ten nude mice (p < 0.05). Significant differences were analyzed using an independent t test. b Image representing the differences in the volume of tumors from nude mice injected with either LV-GFP or LV-ADAR1 cells. c Image of excised tumors from nude mice with LV-ADAR1 or LV-GFP cell injection. d and e ADAR1 and PCNA expression levels were examined by IHC. f SOX2 and POU5F1 expression levels were examined by IHC. Scale bars: 100 μm and 200 μm

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